Mechanisms for Automated Negotiation in State Oriented Domains

This paper lays part of the groundwork for a domain theory of negotiation, that is, a way of classifying interactions so that it is clear, given a domain, which negotiation mechanisms and strategies are appropriate. We define State Oriented Domains, a general category of interaction. Necessary and sufficient conditions for cooperation are outlined. We use the notion of worth in an altered definition of utility, thus enabling agreements in a wider class of joint-goal reachable situations. An approach is offered for conflict resolution, and it is shown that even in a conflict situation, partial cooperative steps can be taken by interacting agents (that is, agents in fundamental conflict might still agree to cooperate up to a certain point). A Unified Negotiation Protocol (UNP) is developed that can be used in all types of encounters. It is shown that in certain borderline cooperative situations, a partial cooperative agreement (i.e., one that does not achieve all agents' goals) might be preferred by all agents, even though there exists a rational agreement that would achieve all their goals. Finally, we analyze cases where agents have incomplete information on the goals and worth of other agents. First we consider the case where agents' goals are private information, and we analyze what goal declaration strategies the agents might adopt to increase their utility. Then, we consider the situation where the agents' goals (and therefore stand-alone costs) are common knowledge, but the worth they attach to their goals is private information. We introduce two mechanisms, one 'strict', the other 'tolerant', and analyze their affects on the stability and efficiency of negotiation outcomes.Comment: See http://www.jair.org/ for any accompanying file

An Agent Based Approach of Collective Foraging

In this paper the behaviour of a bee colony is modeled as a society of communicating agents acting in parallel and synchroniz-ing their behaviour. Two computational models for defining the agents behaviour are introduced and compared and tools developed for these models are briefly illustrated.Ministerio de Ciencia y Tecnología TIC2002-04220-C03-0

Shock-wave thrombus ablation, a new method for noninvasive mechanical thrombolysis

Successful experimental and clinical experience with thrombus ablation has been attained with high-power acoustic energy delivered in a catheter. The goal of this study was to investigate the feasibility of noninvasive thrombus ablation by focused high-power acoustic energy. The source for high-power acoustic energy was a shock-wave generator in a water tank equipped with an acoustic lens with a fixed focal point at 22.5 cm. Thrombus was prepared in vitro, weighed (0.24 +/- 0.08 g), and inserted in excised human femoral artery segments. The arterial segments were ligated, positioned at the focal point and then randomized into either test (n = 8) or control (n = 7). An x-ray system verified the 3-dimensional positioning of the arterial segment at the focal point. A 5 MHz ultrasound imaging system continuously visualized the arterial segment at the focal point before, during and after each experiment. The test segments were exposed to shock waves (1,000 shocks/24 kv). The arterial segment content was then flushed and the residual thrombus weighed. The arterial segment and thrombus were fixed and submitted to histologic examination. The test group achieved a significant ablation of thrombus mass (0.25 +/- 0.15 vs 0.07 +/- 0.003 g; P = 0.0001) after application of shock waves. Arterial segments showed no gross or microscopic damage. Ultrasound imaging revealed a localized (1.9 +/- 0.5 cm2), transient (744 +/- 733 ms), cavitation field at the focal point at the time of application of focused shock waves. Thus, focused high-power acoustic energy can effect noninvasive thrombus ablation without apparent damage to the arterial wall. The mechanism underlying shock-wave thrombus ablation may be associated with the cavitation effect.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/29728/1/0000064.pd

An Agent Architecture for Concurrent Bilateral Negotiations

Abstract. We present an architecture that makes use of symbolic decision-making to support agents participating in concurrent bilateral negotiations. The architecture is a revised version of previous work with the KGP model [23, 12], which we specialise with knowledge about the agent’s self, the negotiation opponents and the environment. Our work combines the specification of domain-independent decision-making with a new protocol for concurrent negotiation that revisits the well-known alternating offers protocol [22]. We show how the decision-making can be specialised to represent the agent’s strategies, utilities and prefer-ences using a Prolog-like meta-program. The work prepares the ground for supporting decision-making in concurrent bilateral negotiations that is more lightweight than previous work and contributes towards a fully developed model of the architecture

INTCare: a knowledge discovery based intelligent decision support system for intensive care medicine

This paper introduces the INTCare system, an intelligent information system based on a completely automated Knowledge Discovery process and on the Agents paradigm. The system was designed to work in Hospital Intensive Care Units, supporting the physicians’ decisions by means of prognostic Data Mining models. In particular, these techniques were used to predict organ failure and mortality assessment. The main intention is to change the current reactive behaviour to a pro-active one, enhancing the quality of service. Current applications and experimentations, the functional and structural aspects, and technological options are presented

Introduction of a new model for time-continuous and non-contact investigations of in-vitro thrombolysis under physiological flow conditions

<p>Abstract</p> <p>Background</p> <p>Thrombolysis is a dynamic and time-dependent process influenced by the haemodynamic conditions. Currently there is no model that allows for time-continuous, non-contact measurements under physiological flow conditions. The aim of this work was to introduce such a model.</p> <p>Methods</p> <p>The model is based on a computer-controlled pump providing variable constant or pulsatile flows in a tube system filled with blood substitute. Clots can be fixed in a custom-built clot carrier within the tube system. The pressure decline at the clot carrier is measured as a novel way to measure lysis of the clot. With different experiments the hydrodynamic properties and reliability of the model were analyzed. Finally, the lysis rate of clots generated from human platelet rich plasma (PRP) was measured during a one hour combined application of diagnostic ultrasound (2 MHz, 0.179 W/cm²) and a thrombolytic agent (rt-PA) as it is commonly used for clinical sonothrombolysis treatments.</p> <p>Results</p> <p>All hydrodynamic parameters can be adjusted and measured with high accuracy. First experiments with sonothrombolysis demonstrated the feasibility of the model despite low lysis rates.</p> <p>Conclusions</p> <p>The model allows to adjust accurately all hydrodynamic parameters affecting thrombolysis under physiological flow conditions and for non-contact, time-continuous measurements. Low lysis rates of first sonothrombolysis experiments are primarily attributable to the high stability of the used PRP-clots.</p